Australia's magic mushrooms collected for medical research (2024)

Australia's first legal collection of native "magic" mushrooms could provide medical options to treat severe depression, alcohol and drug addiction, post-traumatic stress disorder (PTSD), and the fear experienced at the end of terminally ill people's lives.

Key points:

  • This will be Australia's first legal collection of magic mushrooms
  • They will be studied for their psychoactive properties
  • The research could provide the foundation for tailored medical psychedelic treatments.

University of Queensland mycologist and evolutionary biologist Dr Alistair McTaggart has been given approval to collect and catalogue psilocybin mushrooms found growing in cow manure and leaf litter on damp forest floors after rain.

The federal government is investing a total of $15 million in grants to support Australian-led research into the use ofmushrooms, ecstasy and ketamine to combat illnesses such asPTSD, major depressive disorders, addiction and eating disorders.

"Psychedelic mushrooms are taking off, everyone's talking about them," Dr McTaggart said.

"In America the USDA [United States Department of Agriculture]has fast tracked psilocybin treatment.It's considered a breakthrough therapy," Dr McTaggart said.

"With COVID-19 right now, I think there's never been a better time to start looking for therapies for mental health."

Australia's magic mushrooms collected for medical research (1)

Trip into the unknown

Globally, 200 species of mushroom produce psilocybin —a natural psychoactive compound with hallucinogenic effects similar to LSD.

But little is known about the 20-30 species of psychedelicmushrooms in Australia, with Dr McTaggart's research to investigate whether they are native, edible, poisonousor adaptable for medicinal use.

Some, like the golden top mushroom, or Psilocybe cubensis —that is commonly found growing in cow pats —may originate from overseas.

Australia's magic mushrooms collected for medical research (2)

At The University of Queensland, the Queensland Alliance for Agriculture and Food Innovation project will investigate the DNA of the mushrooms and their psychoactive properties.

Dr McTaggart is keen to tap into the knowledge of citizen scientists who photograph fungi and collaborate with researchers interested in cultivating promising genetic strains to tailor-make specific medical treatments.

In Australia, it is illegal to cultivate, possess, use or supply psychedelic mushrooms.

But, like medicinalmarijuana, Dr McTaggart saidthat wouldchange, in line with other countries.

Australia's magic mushrooms collected for medical research (3)

Psychedelic renaissance

Edith Cowan University's school of medical and health sciences psychologist, Dr Stephen Bright, hopes to conduct clinical trials of psilocybin-assisted psychotherapy in Western Australia for treatment resistant depression.

"The research that we're talking about here — in terms of understanding the native psilocybin species — could contribute to the international psychedelic science renaissance," Dr Bright said.

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In 1970, disgraced US president Richard Nixon's "war"on psychedelic drugs froze research into the therapeutic benefits of mushrooms.

Recent international trials at Johns Hopkins Centre for Psychedelic and Consciousness Research have revealed psilocybin's potential.

One treatment session with psychedelics is said to have achieved what years of psychotropic drugs and counselling hadnot been able to accomplish.

However, scientists also stress the risk of mistaking "magic"mushrooms for "deadly"mushrooms and warn that self-medicating hallucinogens for depression or anxiety could actually do people harm.

"It needs to occur in a clinical environment, where there are trained facilitators, psychologists, social workers [and]psychiatrists who are able to set up the right conditions because it can be challenging at times," Dr Bright said.

"With depression, it allows people to consider their core beliefs of who they are as a person, how they relate to other people and where they fit in the worldand those core beliefs are what's driving the depression."

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Dr Bright described psilocybin as a non-addictive drug that couldhelp treat addictions, explaining that people who use mushrooms on a frequent basis become tolerant quickly and do notget any effects from it any more.

"Psilocybin has almost a fail-safe built into it, to make it relatively safe as a drug — provided it's done within the right setting, given the extreme state of consciousness that it produces."

Doctor Tom May is the principal research scientist in mycology at the Royal Botanic Gardens Victoria. Hehas compiled a catalogue of Australian fungi.

He said Dr McTaggart's genomic sequencing work would be important to be able to tell species apart.

"There has been a lot of interest in hallucinogens for many decades, but moving into a laboratory setting means that things can be tested and refined to really work out specific kinds of therapy using specific versions of the different compounds," he said.

Dr McTaggart will also test the hypotheses that the Australian native mushroom Psilocybe subaeruginosa has spread globally to become the most commonly used psilocybin in the medical world.

"This species, or a close relative, is now the foundation of patents and research in Europe and the United States," he said.

Posted, updated

Australia's magic mushrooms collected for medical research (2024)

FAQs

Can mushrooms be used as medicine? ›

They have been used to treat infection for hundreds of years, mostly in Asia. Today, medicinal mushrooms are also used to treat lung diseases and cancer. For more than 30 years, medicinal mushrooms have been approved as an addition to standard cancer treatments in Japan and China.

What are the spores of P subaeruginosa? ›

The spores are smooth, subellipsoid, with an apical germ pore, measuring (10) 13.2–14.3 (15.4) x 6.6–7.7 x 6–7.5 µm.

What is the most medicinal mushroom? ›

Chaga mushroom (scientific name: Inonotus obliquus): It is also called “the king of medicinal mushrooms.” It is not a true mushroom but a mass of mycelia (called sclerotium). This mushroom is rich in various antioxidants. It boosts immunity, brain health and liver health and may thus increase life span.

Which medicinal mushroom is most popular in the world? ›

The Top 7 Medicinal Mushrooms
  • Lion's Mane.
  • Reishi.
  • Cordyceps.
  • Chaga.
  • Turkey Tail.
  • Shiitake.
  • Maitake.
  • Bonus: Oyster, Agaricus, Tremella.

What mushroom explodes spores? ›

Warty, poisonous, explosive. Common earthball might look like a potato, but it is not for eating. Spot it in woodland; you might even see it release its spores as its top ruptures like a gaping mouth to reveal the blackish, powdery spores within.

Do spores have gender? ›

Heterosporous plants, such as seed plants, spikemosses, quillworts, and ferns of the order Salviniales produce spores of two different sizes: the larger spore (megaspore) in effect functioning as a "female" spore and the smaller (microspore) functioning as a "male".

Are there female spores? ›

Spores may be identical isospores or come in different sizes (microspores and megaspores), but strictly speaking, spores and sporophytes are neither male nor female because they do not produce gametes. The alternate generation, the gametophyte, produces gametes, eggs and/or sperm.

What is the medicinal purpose of mushrooms? ›

Mushrooms are a rich, low-calorie source of fiber, protein, and antioxidants. They may also help to lessen the risk of developing serious health conditions, such as Alzheimer's, heart disease, cancer, and diabetes. They're also great sources of: Selenium.

What are the medicinal benefits of mushrooms? ›

7 benefits of eating mushrooms
  • Boost your immune system. Chronic inflammation (long-term swelling) is associated with heart disease, cancer and other medical conditions. ...
  • Lower blood pressure. ...
  • Support weight loss. ...
  • Supply vitamin D. ...
  • Protect brain health. ...
  • Maintain heart health. ...
  • Improve gut health.
Dec 22, 2022

Are medicinal mushrooms legit? ›

It seems the vast majority of health claims made for mushrooms are unsupported by good-quality human trials. Even sceptics acknowledge, however, that absence of evidence is not evidence of absence.

How do you make medicine with mushrooms? ›

The Tincture Recipe
  1. Soak 1/2 of the mushrooms in 190 proof Everclear for 2 weeks, shaking regularly. ...
  2. Strain, retaining mushroom solids, and set aside liquid.
  3. Add unused 1/2 of mushrooms to the alcohol drained mushroom solids and soak in hot water (130-160 degrees) for 12 hours using a crockpot set to warm.
Dec 19, 2020

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